Description

3-tert-Butoxymethylphenylboronic Acid is a specialized organoboron compound that serves as a valuable synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity boronic acid is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl moieties.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical reagent for forming carbon-carbon bonds between aromatic rings, a fundamental transformation in medicinal and process chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Ligand and Catalyst Development: Employed as a precursor for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: A useful monomer or precursor in the development of organic electronic materials, such as those for OLEDs or conductive polymers.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	3-tert-Butoxymethylphenylboronic Acid
CAS No.	858364-78-0
Molecular Formula	C₁₁H₁₇BO₃
Molecular Weight	208.06 g/mol
Synonyms	(3-((tert-Butoxy)methyl)phenyl)boronic Acid; 3-((tert-Butoxymethyl)phenyl)boronic Acid; 3-(tert-Butoxymethyl)benzeneboronic Acid; 3-tert-Butoxymethylbenzeneboronic Acid; B-[3-[(1,1-Dimethylethoxy)methyl]phenyl]boronic Acid; 3-(tert-Butoxy)methylphenylboronic Acid; 3-(tert-Butyloxymethyl)phenylboronic Acid; Boronic acid, B-[3-[(1,1-dimethylethoxy)methyl]phenyl]-
EINECS	Contact for details

Quality Control

Our 3-tert-Butoxymethylphenylboronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, NMR for structural confirmation, and Karl Fischer titration for moisture content. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.