Description

(S)-Boroala-(-)-Pinanediol-Hcl CAS NO 858354-78-6 is a high-purity chiral boronic acid derivative, serving as a critical building block in asymmetric synthesis. Its value lies in providing exceptional stereochemical control for the formation of carbon-carbon bonds, enabling the production of complex, single-enantiomer molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Asymmetric Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing chiral biaryl and other stereogenic centers with high enantioselectivity.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel APIs, especially for oncology, CNS, and cardiovascular drugs.
• Process Chemistry & Scale-up: Employed in the optimization and pilot-scale production of chiral compounds for clinical trials.
• Ligand and Catalyst Development: Serves as a precursor or testing substrate for new chiral ligands and catalysts.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and medicinal chemistry.
• Fine Chemical Manufacturing: Applied in the synthesis of specialty chemicals, agrochemicals, and flavors & fragrances requiring specific chirality.

Basic Information

Product Name	(S)-Boroala-(-)-Pinanediol-Hcl
CAS No.	858354-78-6
Molecular Formula	C₁₅H₂₆BClO₂
Molecular Weight	284.63 g/mol
Synonyms	(S)-(-)-Pinanediol (2-Allylphenyl)boronate Hydrochloride; (S)-2-(2-Allylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Hydrochloride (Pinanediol protected form); (S)-2-Allylbenzeneboronic Acid Pinanediol Ester Hydrochloride; (S)-Boroala Pinanediol Ester HCl; (S)-2-Allylphenylboronic Acid Pinacol Ester Hydrochloride (common misnomer); Boroala(-)-Pinanediol-Hcl, (S)-; (S)-Boroala Pinanediol HCl Salt
EINECS	Contact for details

Quality Control

Our (S)-Boroala-(-)-Pinanediol-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.