Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxaldehyde, 1-[Tris(1-Methylethyl)Silyl]- is a high-value, organosilicon-protected heterocyclic aldehyde building block, essential for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular construction, particularly in the development of complex pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers engaged in creating novel drug candidates and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel pesticides and herbicides with specific biological activity.
• Material Science: Serves as a building block for organic electronic materials and advanced polymers.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Used in scaling up routes for active pharmaceutical ingredients (APIs) requiring this specific protected aldehyde functionality.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxaldehyde, 1-[Tris(1-Methylethyl)Silyl]-
CAS No.	858117-08-5
Molecular Formula	C17H26N2OSi
Molecular Weight	302.49 g/mol
Synonyms	1-Triisopropylsilyl-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde; 1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde; 1-TIPS-7-azaindole-3-carboxaldehyde; 1-TIPS-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde; 1-(Triisopropylsilyl)-7-azaindole-3-carboxaldehyde; 3-Formyl-1-triisopropylsilyl-1H-pyrrolo[2,3-b]pyridine; 1-TIPS-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxaldehyde, 1-[Tris(1-Methylethyl)Silyl]- adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.