Description

3-(2-Propen-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Pyridine is a high-value, functionalized pyridine derivative containing both a vinyl and a pinacol boronate ester group, making it a versatile building block for advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel pharmaceuticals, agrochemicals, and organic electronic materials through cross-coupling reactions. It is primarily sought after by R&D chemists in pharmaceutical development and fine chemical production for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require complex, boronic acid-containing heterocycles.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, ligands for catalysts, and advanced polymers.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of molecular imaging agents.
• Catalyst Ligand Development: The pyridine and boronate functionalities make it useful for designing novel ligands for transition metal catalysis.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	3-(2-Propen-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Pyridine
CAS No.	857934-96-4
Molecular Formula	C14H20BNO2
Molecular Weight	245.13 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-vinylpyridine; 3-Vinyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Ethenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pyridine, 3-ethenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Vinylpyridine-5-boronic acid pinacol ester; 857934-96-4; 3-Allyl-5-(pinacolboronato)pyridine (common misnomer); 5-(Pinacolatoboryl)-3-vinylpyridine
EINECS	Contact for details

Quality Control

Our 3-(2-Propen-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition of the boronate ester moiety.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.