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Phenyl-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Methanol CAS NO 857934-89-5


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CAS No.:857934-89-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Phenyl-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Methanol is a sophisticated boronic ester derivative, a key intermediate in modern synthetic organic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require high-purity building blocks for drug discovery and specialty polymer synthesis.

Application

  • Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
  • Drug Discovery & Medicinal Chemistry: Used in high-throughput screening and the development of novel therapeutic candidates, particularly for creating biaryl and complex aromatic structures.
  • Advanced Material Synthesis: Serves as a monomer or precursor in the production of organic electronic materials, such as those used in OLEDs and organic photovoltaics.
  • Ligand and Catalyst Development: Employed in the research and preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
  • Agrochemical Research: Utilized as an intermediate in the development of new herbicides, fungicides, and plant growth regulators.
  • Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and catalysis at universities and corporate R&D centers.

Basic Information

Product Name Phenyl-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Methanol
CAS No. 857934-89-5
Molecular Formula C19H23BO3
Molecular Weight 310.20 g/mol
Synonyms [3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl](phenyl)methanol; (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(phenyl)methanol; 3-(Hydroxy(phenyl)methyl)phenylboronic acid pinacol ester; 3-(Phenylhydroxymethyl)phenylboronic acid pinacol ester; Boronic acid, B-[3-(hydroxyphenylmethyl)phenyl]-, 1,1-dimethylethyl ester; Pinacol [3-(hydroxy(phenyl)methyl)phenyl]boronate
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Quality Control

Our Phenyl-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance for critical synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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