Description

(S)-Tol-Binap Rucl2 Ampy is a high-performance ruthenium-based chiral catalyst, specifically designed for asymmetric hydrogenation and other enantioselective transformations. This compound is valued for its exceptional stereoselectivity and catalytic efficiency, enabling the production of optically pure intermediates critical for advanced synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and specialty chemicals.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and olefins in pharmaceutical intermediate synthesis.
• Pharmaceutical Manufacturing: Production of chiral active pharmaceutical ingredients (APIs) for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
• Agrochemical Synthesis: Creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Synthesis of specialty flavors, fragrances, and advanced materials requiring high optical purity.
• Academic & Industrial Research: A key tool in methodological development for new catalytic asymmetric reactions.
• Process Chemistry Optimization: Scaling up enantioselective routes for cost-effective and sustainable manufacturing.

Basic Information

Product Name	(S)-Tol-Binap Rucl2 Ampy
CAS No.	857678-55-8
Molecular Formula	C48H42Cl2N2P2Ru
Molecular Weight	882.78 g/mol
Synonyms	(S)-TolBINAP Ru(II) (p-cymene) chloride; Dichloro[(S)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II); (S)-TolBINAP RuCl2(p-cymene); (S)-Tol-BINAP-Ru(II)-p-cymene chloride; RuCl2[(S)-TolBINAP](p-cymene); (S)-TolBINAP Ru catalyst; (S)-TolBINAP RuCl2(Cymene); (S)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl ruthenium p-cymene dichloride
EINECS	Contact for details

Quality Control

Our (S)-Tol-Binap Rucl2 Ampy is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to verify enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. The product is hygroscopic and sensitive to oxidation; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain catalytic activity and purity.

Specification

Item	Specification
Appearance	Reddish-brown to purple crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Ruthenium Content	10.5 - 12.5%
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.