Description

1-(5-Iodo-2-Nitro-Phenyl)-Ethanone is a specialized aromatic ketone building block featuring both iodo and nitro functional groups, which are highly valuable for subsequent chemical transformations. This compound is critical for research and development in advanced organic synthesis, enabling the creation of complex molecules with precision. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic scaffolds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where its functional groups allow for targeted structural modifications.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Organic Synthesis: A versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive iodine substituent, and for reduction or substitution of the nitro group.
• Dye & Pigment Industry: Employed in the synthesis of complex organic dyes and colorants, leveraging its nitro-aromatic structure.
• Academic & Industrial R&D: Essential for method development and exploratory chemistry in university and corporate research settings.

Basic Information

Product Name	1-(5-Iodo-2-Nitro-Phenyl)-Ethanone
CAS No.	857567-50-1
Molecular Formula	C8H6INO3
Molecular Weight	291.05 g/mol
Synonyms	5'-Iodo-2'-nitroacetophenone; 1-(5-Iodo-2-nitrophenyl)ethan-1-one; 2'-Nitro-5'-iodoacetophenone; 5-Iodo-2-nitroacetophenone; Ethanone, 1-(5-iodo-2-nitrophenyl)-; Acetophenone, 5'-iodo-2'-nitro-; 1-Acetyl-5-iodo-2-nitrobenzene; 2-Nitro-5-iodoacetophenone
EINECS	Contact for details

Quality Control

Our 1-(5-Iodo-2-Nitro-Phenyl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.