Description

2-Methyl-4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3-Thiazole is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the precise construction of complex molecular architectures, a critical step in developing advanced materials and pharmaceuticals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create boronic acid-based probes and sensors for detecting biological analytes.
• Polymer Chemistry: Incorporated into polymer backbones to introduce specific functionality or to enable further post-polymerization modification.

Basic Information

Item	Information
Product Name	2-Methyl-4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3-Thiazole
CAS No.	857283-68-2
Molecular Formula	C₁₆H₂₀BNO₂S
Molecular Weight	301.21 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylphenylthiazole; 2-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]thiazole; 2-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)thiazole; 857283-68-2; Thiazole boronic acid pinacol ester; 4-(2-Methylthiazol-4-yl)phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our 2-Methyl-4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3-Thiazole undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, critical for reproducible cross-coupling performance. Our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced material research. A comprehensive Certificate of Analysis (COA) detailing purity (HPLC/NMR), identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.