Description

1,2,3,6-Tetrahydropyridine-4-Yl-Boronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, especially those containing heterocyclic scaffolds for central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the boronic acid functionality allows for precise structural modifications.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a pivotal coupling partner for the introduction of the tetrahydropyridine moiety into target molecules, a common motif in medicinal chemistry.
• Material Science Research: Employed in the creation of novel organic electronic materials and ligands for catalysis.
• Chemical Biology & Proteomics: Utilized in the development of chemical probes and inhibitors for studying biological pathways.
• Academic & Contract Research: Serves as a valuable reagent for method development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	1,2,3,6-Tetrahydropyridine-4-Yl-Boronic Acid
CAS No.	856694-87-6
Molecular Formula	C5H10BNO2
Molecular Weight	126.95 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydro-4-pyridineboronic acid; 4-Borono-1,2,3,6-tetrahydropyridine; Tetrahydropyridin-4-ylboronic acid; 1,2,3,6-Tetrahydro-4-pyridinylboronic acid; 4-Pyridineboronic acid, 1,2,3,6-tetrahydro-; B-(1,2,3,6-Tetrahydro-4-pyridinyl)boronic acid
EINECS	Contact for details

Quality Control

Our 1,2,3,6-Tetrahydropyridine-4-Yl-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.