Description

(-)-9-(1R,2R-Pseudoephedrinyl)-(10S)-(Trimethylsilyl)-9-Borabicyclo[3.3.2]Decane is a highly specialized, enantiomerically pure organoboron reagent derived from pseudoephedrine. This compound matters as a powerful chiral auxiliary and catalyst for asymmetric synthesis, enabling the production of single-enantiomer intermediates critical for advanced pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex, stereodefined molecular architectures.

Application

• Asymmetric Hydroboration: A key chiral catalyst for the enantioselective hydroboration of prochiral alkenes, yielding chiral boronic esters.
• Pharmaceutical Intermediate Synthesis: Enables the stereocontrolled synthesis of chiral active pharmaceutical ingredients (APIs) and complex natural products.
• Chiral Ligand Precursor: Serves as a building block for developing novel chiral ligands used in transition metal catalysis.
• Asymmetric Reduction: Employed in the enantioselective reduction of ketones and imines to produce chiral alcohols and amines.
• Methodology Development: A valuable tool for academic and industrial research in developing new asymmetric synthetic methodologies.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.

Basic Information

Item	Details
Product Name	(-)-9-(1R,2R-Pseudoephedrinyl)-(10S)-(Trimethylsilyl)-9-Borabicyclo[3.3.2]Decane
CAS No.	856676-11-4
Molecular Formula	C₂₁H₃₆BNOSi
Molecular Weight	369.41 g/mol
Synonyms	(-)-9-(1R,2R-Pseudoephedrinyl)-(10S)-(Trimethylsilyl)-9-Borabicyclo[3.3.2]decane; (1R,2R)-(-)-Pseudoephedrine-Derived Chiral Borane Reagent; TMS-Substituted Chiral 9-BBN Derivative; Chiral Organoboron Reagent 856676-11-4; Asymmetric Hydroboration Catalyst; Pseudoephedrine-Borane Complex; (10S)-Trimethylsilyl-9-borabicyclo[3.3.2]decane Pseudoephedrine Adduct
EINECS	Contact for details

Quality Control

Every batch of our (-)-9-(1R,2R-Pseudoephedrinyl)-(10S)-(Trimethylsilyl)-9-Borabicyclo[3.3.2]Decane is manufactured and tested under strict quality management systems to ensure high enantiomeric purity and chemical integrity. Our products undergo rigorous quality testing, including chiral HPLC and NMR spectroscopy, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its moisture-sensitive and easily oxidized nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed and allowed to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.