Description

2-Bromo-5-Iodo-1,3-Bis(1-Methylethyl)-Benzene is a highly functionalized, multi-halogenated aromatic compound with a unique sterically hindered structure. This compound serves as a critical advanced intermediate for the synthesis of complex organic molecules, particularly in the development of pharmaceuticals and specialty materials. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting complex small molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where its halogenated, hindered structure can impart specific biological activity.
• Ligand Synthesis: Serves as a precursor for creating sterically demanding ligands used in catalysis, such as for cross-coupling reactions.
• Material Science: Employed in the research and development of organic electronic materials, liquid crystals, and polymers requiring tailored aromatic cores.
• Cross-Coupling Reactions: The bromine and iodine substituents offer orthogonal reactivity for sequential Suzuki, Stille, or Sonogashira cross-coupling reactions to build complex biaryl systems.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and for creating compound libraries for high-throughput screening.

Basic Information

Product Name	2-Bromo-5-Iodo-1,3-Bis(1-Methylethyl)-Benzene
CAS No.	856197-47-2
Molecular Formula	C12H16BrI
Molecular Weight	367.07 g/mol
Synonyms	1-Bromo-4-Iodo-2,6-Diisopropylbenzene; 2,6-Diisopropyl-1-bromo-4-iodobenzene; 1-Bromo-2,6-bis(1-methylethyl)-4-iodobenzene; 4-Bromo-1-iodo-2,6-diisopropylbenzene; 2-Bromo-5-iodo-1,3-diisopropylbenzene; 2,6-Diisopropyl-4-iodo-1-bromobenzene; Benzene, 1-bromo-4-iodo-2,6-bis(1-methylethyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Iodo-1,3-Bis(1-Methylethyl)-Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.