Description

5-(2-Chlorophenyl)Nicotinaldehyde is a high-purity organic building block featuring a chlorophenyl-substituted nicotinaldehyde core structure. This compound matters as a versatile and critical intermediate for synthesizing complex molecules in advanced research and development. Pharmaceutical, agrochemical, and material science industries need it for creating novel active ingredients and functional materials. Its unique structure enables the introduction of both aldehyde and aromatic chloride functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic system.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis and Contract Manufacturing: A requested intermediate for bespoke chemical synthesis services targeting specialized end-products.

Basic Information

Product Name	5-(2-Chlorophenyl)Nicotinaldehyde
CAS No.	855301-00-7
Molecular Formula	C12H8ClNO
Molecular Weight	217.65 g/mol
Synonyms	5-(2-Chlorophenyl)pyridine-3-carbaldehyde; 3-Formyl-5-(2-chlorophenyl)pyridine; 2-Chloro-5-pyridinylbenzaldehyde; Nicotinaldehyde, 5-(2-chlorophenyl)-; 5-(2-Chlorophenyl)-3-pyridinecarboxaldehyde; 5-(o-Chlorophenyl)nicotinaldehyde; Pyridine-3-carbaldehyde, 5-(2-chlorophenyl)-
EINECS	Contact for details

Quality Control

Our 5-(2-Chlorophenyl)Nicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.