Description

2-Bromo-1-(Isoxazol-3-Yl)Ethanone is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its reactive bromoacetyl group attached to an isoxazole scaffold, making it a key precursor for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole moiety.
• Chemical Biology Probe Synthesis: Serves as a starting material for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	2-Bromo-1-(Isoxazol-3-Yl)Ethanone
CAS No.	855292-87-4
Molecular Formula	C5H4BrNO2
Molecular Weight	189.99 g/mol
Synonyms	3-Acetylisoxazol-5-yl Bromide; 2-Bromo-1-(3-isoxazolyl)ethanone; 2-Bromo-1-(1,2-oxazol-3-yl)ethan-1-one; 3-(Bromoacetyl)isoxazole; Ethanone, 2-bromo-1-(3-isoxazolyl)-; Bromo(3-isoxazolyl)methanone
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(Isoxazol-3-Yl)Ethanone is produced and tested under strict quality management protocols to ensure consistency and reliability for your research and development processes. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) are available for each lot upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.