Description

1,2-Bis((2S,5S)-2,5-Dimethylphospholano)Ethane(Cyclooctadiene)Rhodium(I) Trifluoromethanesulfonate is a high-purity, chiral organorhodium complex widely recognized as a highly efficient and enantioselective catalyst. Its value lies in enabling precise asymmetric transformations, which are critical for producing single-enantiomer intermediates and active pharmaceutical ingredients (APIs). This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance catalysts for hydrogenation and other transition metal-catalyzed reactions.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical synthesis.
• Chiral Intermediate Production: In the manufacture of single-enantiomer drug substances and agrochemicals.
• Process Chemistry & Scale-up: Used in pilot plant and commercial-scale production of optically pure compounds.
• Academic & Industrial R&D: A key reagent for developing new asymmetric synthetic methodologies.
• Fine Chemical Synthesis: For the preparation of complex, high-value specialty chemicals requiring precise stereocontrol.

Basic Information

Product Name	1,2-Bis((2S,5S)-2,5-Dimethylphospholano)Ethane(Cyclooctadiene)Rhodium(I) Trifluoromethanesulfonate
CAS No.	854920-90-4
Molecular Formula	C₂₂H₃₈F₃O₃P₂RhS
Molecular Weight	616.43 g/mol
Synonyms	(S,S)-Et-DuPhos Rh(COD)OTf; [Rh((S,S)-Et-DuPhos)(COD)]OTf; Rhodium(I)-(S,S)-1,2-bis(2,5-dimethylphospholano)ethane(1,5-cyclooctadiene) trifluoromethanesulfonate; (S,S)-1,2-Bis(2,5-dimethylphospholano)ethane(1,5-cyclooctadiene)rhodium(I) triflate; DuPhos-Rh Catalyst; Chiral DuPhos Rhodium Complex; Asymmetric Hydrogenation Catalyst Rh-Et-DuPhos
EINECS	Contact for details

Quality Control

Every batch of our chiral catalyst is produced and tested under strict quality management to ensure exceptional purity and consistent catalytic performance. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as Rhodium content, enantiomeric purity of the ligand, and solvent residues. Our quality systems support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air or moisture will degrade performance.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Rhodium Content	Contact for details
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.