Description

2-Ethoxy-3-Pyridineboronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, facilitating the synthesis of complex heterocyclic target molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific pyridine-based structures.
• Suzuki-Miyaura Cross-Coupling: A pivotal reagent for palladium-catalyzed cross-coupling reactions to create biaryl and heterobiaryl structures, which are prevalent in many functional molecules.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and inhibitors for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic acid derivatives.

Basic Information

Product Name	2-Ethoxy-3-Pyridineboronic Acid
CAS No.	854373-97-0
Molecular Formula	C7H10BNO3
Molecular Weight	166.97 g/mol
Synonyms	(2-Ethoxypyridin-3-yl)boronic Acid; 3-Borono-2-ethoxypyridine; 2-Ethoxy-3-pyridinylboronic Acid; 2-Ethoxy-3-pyridylboronic Acid; 2-Ethoxy-pyridine-3-boronic Acid; 3-Pyridineboronic Acid, 2-ethoxy-; Boronic acid, B-(2-ethoxy-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-3-Pyridineboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.