Description

Urea, n-Ethyl-N'-[2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a specialized organic compound featuring a urea core functionalized with an ethyl group and a pinacol boronate ester-substituted phenyl ring. This molecular architecture makes it a versatile and valuable building block in modern synthetic chemistry, particularly for cross-coupling reactions. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic ester precursor for constructing biaryl and heterobiaryl structures central to drug discovery.
• Pharmaceutical Intermediate: Used in the research and synthesis of potential active pharmaceutical ingredients (APIs), especially those requiring complex urea-based pharmacophores.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Can be utilized as a probe or linker in the study of protein interactions and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	Urea, n-Ethyl-N'-[2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	854074-34-3
Molecular Formula	C₁₆H₂₅BN₂O₃
Molecular Weight	304.19 g/mol
Synonyms	1-Ethyl-3-[2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; N-Ethyl-N'-(2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylphenyl Ethyl Urea; Boronic ester functionalized urea derivative; Pinacol boronate urea derivative
EINECS	Contact for details

Quality Control

Our Urea, n-Ethyl-N'-[2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.