Description

4-(5-Phenylthiophen-2-Yl)Butanoic Acid is a high-purity organic building block featuring a phenyl-substituted thiophene core linked to a butanoic acid chain. This compound matters as a versatile and critical intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as drug discovery and material science research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the thiophene moiety for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of conductive polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Ligand Synthesis: The carboxylic acid group allows for derivatization into chelating ligands for catalysis or metal-organic complexes.
• Fluorescent Probe Development: The conjugated thiophene-phenyl system makes it a candidate scaffold for developing organic fluorescent dyes and sensors.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including cross-coupling reactions and heterocyclic chemistry research.

Basic Information

Product Name	4-(5-Phenylthiophen-2-Yl)Butanoic Acid
CAS No.	853921-26-3
Molecular Formula	C14H14O2S
Molecular Weight	246.32 g/mol
Synonyms	4-(5-Phenyl-2-thienyl)butanoic acid; 4-(5-Phenylthiophen-2-yl)butyric acid; 5-Phenyl-2-thiophenebutanoic acid; 853921-26-3; Butanoic acid, 4-(5-phenyl-2-thienyl)-; 4-(5-Phenyl-2-thienyl)butyric acid; 2-Thiophenebutanoic acid, 5-phenyl-; 4-(5-Phenylthien-2-yl)butanoic acid
EINECS	Contact for details

Quality Control

Our 4-(5-Phenylthiophen-2-Yl)Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.