Description

trans-(S)-2-[[3,5-Dimethyl-4-(4-Hydroxy-3-Isopropylbenzyl)Phenoxy]Methyl]-4-(3-Chlorophenyl)-2-Oxo-[1,3,2]Dioxaphosphorinane CAS NO 852948-13-1 is a high-purity, chiral organophosphorus compound characterized by its complex, multi-ring structure. This compound is of significant value as a specialized intermediate or ligand in advanced chemical synthesis, particularly for the development of pharmaceuticals and agrochemicals where stereochemical control is critical. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring high stereoselectivity.
• Catalyst Ligand: Potential use as a sophisticated ligand in asymmetric catalysis to induce chirality in synthetic reactions.
• Agrochemical Research: Intermediate in the development of new-generation, targeted pesticides and herbicides.
• Chemical Biology Probe: Tool compound for studying enzyme mechanisms or biological pathways involving phosphoester chemistry.
• Material Science Research: Monomer or additive for specialized polymers with unique thermal or optical properties.
• Process Chemistry Development: Used in route scouting and optimization for the commercial-scale production of complex molecules.

Basic Information

Product Name	trans-(S)-2-[[3,5-Dimethyl-4-(4-Hydroxy-3-Isopropylbenzyl)Phenoxy]Methyl]-4-(3-Chlorophenyl)-2-Oxo-[1,3,2]Dioxaphosphorinane
CAS No.	852948-13-1
Molecular Formula	C30H34ClO5P
Molecular Weight	541.02 g/mol
Synonyms	(S)-2-[[3,5-Dimethyl-4-(4-Hydroxy-3-Isopropylbenzyl)Phenoxy]Methyl]-4-(3-Chlorophenyl)-2-Oxo-1,3,2-dioxaphosphorinane; trans-(S)-Dioxaphosphorinane derivative; 852948-13-1; (S)-enantiomer of the phosphorinane compound; 2-Oxo-1,3,2-dioxaphosphorinane, 2-[[[3,5-dimethyl-4-[[4-hydroxy-3-(1-methylethyl)phenyl]methyl]phenoxy]methyl]-4-(3-chlorophenyl)-, (2S,4R)-rel-; Phosphorus heterocycle intermediate
EINECS	Contact for details

Quality Control

Our trans-(S)-2-[[3,5-Dimethyl-4-(4-Hydroxy-3-Isopropylbenzyl)Phenoxy]Methyl]-4-(3-Chlorophenyl)-2-Oxo-[1,3,2]Dioxaphosphorinane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity, NMR for structural confirmation, and precise assay determination. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.