Description

2-Chloro-1-(3-Fluoro-4-Methoxyphenyl)Ethanone is a high-purity, specialized aromatic ketone building block of significant importance in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a critical intermediate for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its fluorinated aromatic core for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for advanced organic electronic materials, where its molecular structure can be incorporated into charge-transport or emissive layers.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and the exploration of new chemical spaces in heterocyclic and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Chloro-1-(3-Fluoro-4-Methoxyphenyl)Ethanone
CAS No.	852389-09-4
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	2-Chloro-1-(3-fluoro-4-methoxyphenyl)ethan-1-one; 3'-Fluoro-4'-methoxy-2-chloroacetophenone; 2-Chloro-3'-fluoro-4'-methoxyacetophenone; 1-(3-Fluoro-4-methoxyphenyl)-2-chloroethanone; α-Chloro-3-fluoro-4-methoxyacetophenone; 852389-09-4; 2-Chloro-3-fluoro-4-methoxyacetophenone
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-1-(3-Fluoro-4-Methoxyphenyl)Ethanone is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade meets high-purity specifications suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.