Description

2,5-Dibromopyridine-3-Boronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through cross-coupling reactions.
• Chemical Biology & Diagnostics: Employed in the synthesis of molecular probes, tags, and ligands for studying biological processes and developing diagnostic assays.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in academic laboratories and CROs (Contract Research Organizations).
• Scale-up & Process Chemistry: Suitable for optimization and scale-up from milligram to kilogram quantities for pre-clinical and early-phase clinical material supply.

Basic Information

Product Name	2,5-Dibromopyridine-3-Boronic Acid Pinacol Ester
CAS No.	852228-17-2
Molecular Formula	C11H12BBr2NO2
Molecular Weight	360.84 g/mol
Synonyms	(3-((4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl))-2,5-dibromopyridine; 2,5-Dibromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2,5-Dibromopyridine-3-boronic acid pinacol ester; 3-Borono-2,5-dibromopyridine pinacol ester; Pyridine, 2,5-dibromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2,5-Dibromo-3-pyridineboronic acid pinacol ester; 852228-17-2
EINECS	Contact for details

Quality Control

Our 2,5-Dibromopyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, which is critical for sensitive cross-coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C (refrigerated) for long-term stability, although the material is stable at room temperature for short periods. Keep the container tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.