Description

2-(Piperidin-1-Yl)Pyridine-5-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and advanced materials research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for creating active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of novel crop protection agents and herbicides.
• Material Science & OLED Development: Serves as a precursor for constructing organic semiconductors, light-emitting materials, and other functional polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via parallel and combinatorial chemistry.
• Catalyst Ligand Synthesis: Can be utilized in the preparation of novel ligands for transition metal catalysis.

Basic Information

Product Name	2-(Piperidin-1-Yl)Pyridine-5-Boronic Acid Pinacol Ester
CAS No.	852228-08-1
Molecular Formula	C16H25BN2O2
Molecular Weight	288.20 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(1-piperidinyl)pyridine; 2-Piperidin-1-yl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(1-Piperidinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Piperidino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pyridine, 2-(1-piperidinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 852228-08-1; 2-(Piperidin-1-yl)pyridine-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-1-Yl)Pyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.