Description

1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Piperidine is a high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and boronic acids/esters, crucial for synthesizing biaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially those containing piperidine and biphenyl motifs.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology & Medicinal Chemistry: Facilitates the creation of molecular probes and libraries for drug discovery through high-throughput screening.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, functionalized piperidine derivatives.

Basic Information

Product Name	1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Piperidine
CAS No.	852227-96-4
Molecular Formula	C17H26BNO2
Molecular Weight	287.21 g/mol
Synonyms	4-(Piperidin-1-yl)phenylboronic acid pinacol ester; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine; 4-(1-Piperidinyl)benzeneboronic acid pinacol ester; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine; 4-Piperidin-1-ylbenzeneboronic acid pinacol ester; 1-(4-Pinacolatoboronphenyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Piperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronic ester group. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.