Description

2-(2-Isopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity organoboron reagent, specifically a pinacol boronic ester, widely used in modern synthetic chemistry. Its primary value lies in enabling efficient and selective carbon-carbon bond formation, which is fundamental to constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it serves as a key building block in Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for constructing biaryl and heterobiaryl motifs found in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific aromatic frameworks.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air-handleable boronic ester partner for palladium-catalyzed couplings with aryl halides or triflates.
• Chemical Biology & Medicinal Chemistry: Facilitates the rapid exploration of structure-activity relationships (SAR) through efficient library synthesis.
• Catalyst & Ligand Preparation: Used as a precursor for synthesizing specialized ligands and organometallic catalysts.

Basic Information

Product Name	2-(2-Isopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	852110-33-9
Molecular Formula	C15H23BO2
Molecular Weight	246.15 g/mol
Synonyms	2-Isopropylphenylboronic acid pinacol ester; (2-Isopropylphenyl)boronic acid pinacol ester; 2-(2-Isopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Isopropylphenyl)BPin; Pinacol (2-isopropylphenyl)boronate; 1-Isopropyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; o-Isopropylphenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(2-Isopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including NMR, HPLC, and GC analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged manipulations or when opening containers for the first time to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.