Description

8-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline is a high-value, organoboron building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel quinoline-based drug candidates and APIs.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Ligand Synthesis: Serves as a starting material for the preparation of sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological processes and target engagement.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	8-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline
CAS No.	851985-96-1
Molecular Formula	C₁₉H₂₄BNO₂
Molecular Weight	309.21 g/mol
Synonyms	8-Methylquinolin-7-ylboronic acid pinacol ester; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-8-methylquinoline; 8-Methyl-7-quinolineboronic acid pinacol ester; 8-Methyl-7-(pinacolboranyl)quinoline; Quinoline, 8-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 851985-96-1; 8-Methyl-7-boronic acid pinacol ester quinoline
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere such as nitrogen or argon to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.