Description

7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline CAS NO 851985-81-4 is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in its role as a key boronic ester derivative, enabling critical cross-coupling reactions for the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex quinoline-based structures.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and emissive layer components in display and lighting technologies.
• Material Science: Employed in the creation of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs).
• Chemical Biology & Medicinal Chemistry: Facilitates the synthesis of molecular probes, enzyme inhibitors, and compound libraries for drug discovery.
• Catalyst Ligand Synthesis: Used to prepare sophisticated ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline
CAS No.	851985-81-4
Molecular Formula	C₁₅H₂₀BNO₂
Molecular Weight	257.14 g/mol
Synonyms	7-Quinolineboronic acid pinacol ester; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline; Quinolin-7-ylboronic acid pinacol ester; 7-(Pinacolatoboryl)quinoline; 7-Quinolinylboronic Acid Pinacol Ester; 7-Boronquinoline Pinacol Ester; 851985-81-4
EINECS	Contact for details

Quality Control

Our 7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.