Description

Boronic Acid, B-[2,6-Dichloro-3-(Hydroxymethyl)Phenyl]- is a high-purity, synthetically valuable organoboron building block. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in constructing novel herbicide and fungicide molecules through palladium-catalyzed cross-coupling.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology: Employed in the synthesis of probes and inhibitors for studying enzyme function and biological pathways.
• Catalyst Ligand Precursor: Can be modified to create specialized ligands for transition metal catalysis.
• Custom Synthesis: An essential building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	Boronic Acid, B-[2,6-Dichloro-3-(Hydroxymethyl)Phenyl]-
CAS No.	851756-55-3
Molecular Formula	C7H7BCl2O3
Molecular Weight	220.85 g/mol
Synonyms	(2,6-Dichloro-3-(hydroxymethyl)phenyl)boronic acid; 3-(Hydroxymethyl)-2,6-dichlorobenzeneboronic acid; 2,6-Dichloro-3-(hydroxymethyl)benzeneboronic acid; B-(2,6-Dichloro-3-(hydroxymethyl)phenyl)boronic acid; 2,6-Dichloro-3-(hydroxymethyl)phenylboronic acid; Boronic acid, B-[2,6-dichloro-3-(hydroxymethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[2,6-Dichloro-3-(Hydroxymethyl)Phenyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and lot-to-lot consistency suitable for sensitive coupling reactions. Certificates of Analysis (COA) with full traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.