Description

2,2-Difluoro-n-(2-Hydroxyethyl)Propionamide is a specialized fluorinated amide compound that serves as a valuable building block in advanced organic synthesis. Its unique structure, featuring both difluoro and hydroxyethyl functional groups, makes it a critical intermediate for creating molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoro group can improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and coatings with unique surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes and tags for studying biological mechanisms and diagnostics.
• Organic Electronics: Investigated as a component in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Item	Details
Product Name	2,2-Difluoro-n-(2-Hydroxyethyl)Propionamide
CAS No.	851728-91-1
Molecular Formula	C5H9F2NO2
Molecular Weight	153.13 g/mol
Synonyms	2,2-Difluoro-N-(2-hydroxyethyl)propanamide; N-(2-Hydroxyethyl)-2,2-difluoropropionamide; 2,2-Difluoropropionic acid 2-hydroxyethylamide; 851728-91-1; Propanamide, 2,2-difluoro-N-(2-hydroxyethyl)-; Difluoro-hydroxyethylpropionamide
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluoro-n-(2-Hydroxyethyl)Propionamide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive R&D and scale-up processes. A detailed Certificate of Analysis (COA) including results for assay, purity (by HPLC), and identification is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.