Description

Oxirane, (2,4-Difluorophenyl)-, (2S)- is a high-value, chiral epoxide building block of significant interest in advanced organic synthesis. Its core value lies in providing a stereochemically defined, fluorinated aromatic scaffold that is crucial for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where the introduction of fluorine atoms and specific stereochemistry is required.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), especially in CNS, anti-infective, and oncology drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorinated aromatic groups enhance efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with unique optical or surface properties.
• Fluorine Chemistry Studies: A valuable substrate for investigating novel fluorination reactions and the effects of fluorine substitution on reaction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specific chiral motif.

Basic Information

Product Name	Oxirane, (2,4-Difluorophenyl)-, (2S)-
CAS No.	851634-78-1
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	(2S)-2-(2,4-Difluorophenyl)oxirane; (S)-2-(2,4-Difluorophenyl)oxirane; (-)-2-(2,4-Difluorophenyl)oxirane; (S)-2,4-Difluorostyrene oxide; (S)-1,2-Epoxy-2-(2,4-difluorophenyl)ethane; (2S)-2-(2,4-Difluorophenyl)ethylene oxide; (S)-2,4-DFSO; (S)-2,4-Difluorophenyl glycidol (precursor form)
EINECS	Contact for details

Quality Control

Our Oxirane, (2,4-Difluorophenyl)-, (2S)- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chiral purity and chemical integrity, meeting the exacting standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain product stability. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.