Description

n-[(3Beta)-3-Hydroxy-28-Oxoolean-12-En-28-Yl]-Glycine is a high-purity, semi-synthetic triterpenoid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel bioactive agents targeting a range of therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in drug discovery programs. The consistent quality and reliable supply of this specialized chemical are paramount for ensuring reproducible experimental results and accelerating development timelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathway for novel triterpenoid-based drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control in the production of related active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) of oleanane-type triterpenoids for various biological targets.
• Lead Compound Optimization: Serves as a starting point for medicinal chemistry programs aimed at enhancing pharmacokinetic properties or therapeutic efficacy.
• Academic Research: Utilized in university and institutional labs for fundamental research in natural product chemistry and pharmacology.
• Standards for Regulatory Submission: Provides a characterized material for use in stability studies and regulatory filings for new drug applications.

Basic Information

Product Name	n-[(3Beta)-3-Hydroxy-28-Oxoolean-12-En-28-Yl]-Glycine
CAS No.	851475-58-6
Molecular Formula	C32H49NO5
Molecular Weight	527.74 g/mol
Synonyms	Glycine, N-[(3β)-3-hydroxy-28-oxoolean-12-en-28-yl]-; (3β)-3-Hydroxy-28-oxoolean-12-en-28-yl-glycine; Olean-12-en-28-oic acid, 3-hydroxy-, 28-(aminocarbonylmethyl) ester; 28-(Carboxymethylamino)-3-hydroxyolean-12-en-28-oate; A glycine conjugate of 3-hydroxyoleanolic acid derivative
EINECS	Contact for details

Quality Control

Every batch of n-[(3Beta)-3-Hydroxy-28-Oxoolean-12-En-28-Yl]-Glycine is manufactured and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client or regulatory requirements. We are committed to supplying materials that support the stringent needs of GMP-compliant research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.