Description

4'-Ethoxy-3'-(Trifluoromethyl)Acetophenone, 97% is a high-purity organic building block characterized by its ethoxy and trifluoromethyl substituents on the acetophenone core. This compound matters as a versatile and critical intermediate for synthesizing complex molecules, where the trifluoromethyl group is prized for its ability to modulate lipophilicity, metabolic stability, and binding affinity. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly in medicinal chemistry for lead optimization and in the creation of advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Used in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes, where specific aromatic ketones are required.
• Advanced Material Monomers: Acts as a building block for polymers and advanced materials with tailored thermal and chemical resistance properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for methodology development, cross-coupling reactions, and as a ligand precursor in catalysis.
• Flavor & Fragrance Industry: Potential use in the synthesis of complex aromatic compounds for specialty fragrance applications.

Basic Information

Product Name	4'-Ethoxy-3'-(Trifluoromethyl)Acetophenone, 97%
CAS No.	851263-13-3
Molecular Formula	C11H11F3O2
Molecular Weight	232.20 g/mol
Synonyms	1-[4-Ethoxy-3-(trifluoromethyl)phenyl]ethanone; 4'-Ethoxy-3'-trifluoromethylacetophenone; 3'-Trifluoromethyl-4'-ethoxyacetophenone; 1-(4-Ethoxy-3-(trifluoromethyl)phenyl)ethan-1-one; Ethanone, 1-[4-ethoxy-3-(trifluoromethyl)phenyl]-; 4-Ethoxy-α,α,α-trifluoro-m-acetophenone; p-Ethoxy-m-(trifluoromethyl)acetophenone
EINECS	Contact for details

Quality Control

Our 4'-Ethoxy-3'-(Trifluoromethyl)Acetophenone, 97% is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the specified standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.