Description

4'-Methyl-3'-(Trifluoromethyl)Acetophenone is a high-value trifluoromethylated aromatic ketone, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a methyl and a trifluoromethyl group on the acetophenone core, makes it indispensable for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting applications.
• Advanced Polymer Chemistry: Employed as a monomer or modifier to create specialty polymers with unique thermal, chemical, or surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new fluorination chemistry and constructing complex molecular architectures.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments that offer improved lightfastness and color properties.

Basic Information

Item	Details
Product Name	4'-Methyl-3'-(Trifluoromethyl)Acetophenone
CAS No.	851262-98-1
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	1-[4-Methyl-3-(trifluoromethyl)phenyl]ethanone; 3'-Trifluoromethyl-4'-methylacetophenone; 4-Methyl-3-(trifluoromethyl)acetophenone; 3-(Trifluoromethyl)-4-methylacetophenone; 4-Methyl-α,α,α-trifluoro-m-acetophenone; 1-(4-Methyl-3-(trifluoromethyl)phenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Every batch of 4'-Methyl-3'-(Trifluoromethyl)Acetophenone is manufactured under strict quality management protocols. We ensure consistent high purity and identity through comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.