Description

[3-(4-Chlorophenyl)-5-Mercapto-4H-1,2,4-Triazol-4-Yl]Acetic Acid is a high-purity, heterocyclic organic compound featuring a triazole core functionalized with a chlorophenyl group and a mercapto moiety, serving as a versatile and critical building block in advanced chemical synthesis. Its molecular architecture makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise structural control is paramount. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in antimicrobial, antiviral, and anti-inflammatory therapeutic classes.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new heterocyclic chemistry, ligand design, and material science applications.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scalable synthesis of complex APIs requiring the specific 1,2,4-triazole pharmacophore.
• Coordination Chemistry: Acts as a potential ligand for metal complexes due to the presence of nitrogen and sulfur donor atoms.

Basic Information

Product Name	[3-(4-Chlorophenyl)-5-Mercapto-4H-1,2,4-Triazol-4-Yl]Acetic Acid
CAS No.	851116-15-9
Molecular Formula	C10H8ClN3O2S
Molecular Weight	269.71 g/mol
Synonyms	4-(Carboxymethyl)-3-(4-chlorophenyl)-1H-1,2,4-triazole-5-thiol; 2-[[3-(4-Chlorophenyl)-5-sulfanyl-1,2,4-triazol-4-yl]]acetic acid; (3-(4-Chlorophenyl)-5-mercapto-4H-1,2,4-triazol-4-yl)acetic acid; 4-(4-Chlorophenyl)-2,4-dihydro-5-mercapto-3H-1,2,4-triazol-3-one-4-acetic acid (tautomer); 851116-15-9; 4-(Carboxymethyl)-3-(p-chlorophenyl)-δ²-1,2,4-triazoline-5-thione
EINECS	Contact for details

Quality Control

Our production of [3-(4-Chlorophenyl)-5-Mercapto-4H-1,2,4-Triazol-4-Yl]Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specification results are provided with every shipment. We support compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.