Description

6-[4-(Trifluoromethoxy)Phenyl]-3-Pyridinecarbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridinecarbaldehyde core and trifluoromethoxy-substituted aromatic ring. This compound matters for its critical role as a versatile building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring fluorinated molecular architectures to enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel Active Pharmaceutical Ingredients (APIs), especially in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Research: Serves as a building block for creating new generation pesticides and herbicides, where the trifluoromethoxy group can improve lipophilicity and biological activity.
• Material Science: Used in the synthesis of specialized ligands and monomers for advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis: Functions as a versatile aldehyde component in cross-coupling reactions, condensations, and reductive amination for creating complex molecular libraries.

Basic Information

Product Name	6-[4-(Trifluoromethoxy)Phenyl]-3-Pyridinecarbaldehyde
CAS No.	851069-97-1
Molecular Formula	C13H8F3NO2
Molecular Weight	267.21 g/mol
Synonyms	3-Formyl-6-[4-(trifluoromethoxy)phenyl]pyridine; 6-(4-Trifluoromethoxyphenyl)pyridine-3-carboxaldehyde; 6-(4-(Trifluoromethoxy)phenyl)nicotinaldehyde; 3-Pyridinecarboxaldehyde, 6-[4-(trifluoromethoxy)phenyl]-; 851069-97-1; 6-(4-Trifluoromethoxyphenyl)-3-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 6-[4-(Trifluoromethoxy)Phenyl]-3-Pyridinecarbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere to prevent oxidation and kept away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.