Description

1-Chloro-5-Iodo-4-Methoxy-2-Methyl-Benzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting complex aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where specific halogen substitution patterns are required for bioactivity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Sonogashira, and Buchwald-Hartwig aminations due to the presence of both chloro and iodo substituents.
• Chemical Biology & Proteomics: Can be utilized as a reagent for bioconjugation or as a tag in probe development for studying biological systems.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	1-Chloro-5-Iodo-4-Methoxy-2-Methyl-Benzene
CAS No.	850864-46-9
Molecular Formula	C8H8ClIO
Molecular Weight	282.51 g/mol
Synonyms	2-Chloro-4-iodo-5-methoxytoluene; 4-Chloro-2-iodo-5-methylanisole; 5-Chloro-1-iodo-2-methoxy-4-methylbenzene; 1-Chloro-5-iodo-4-methoxy-2-methylbenzene; 850864-46-9; 4-Methoxy-2-methyl-1-chloro-5-iodobenzene; 2-Methyl-4-methoxy-1-chloro-5-iodobenzene; Benzene, 1-chloro-5-iodo-4-methoxy-2-methyl-
EINECS	Contact for details

Quality Control

Our 1-Chloro-5-Iodo-4-Methoxy-2-Methyl-Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, GC, and NMR, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.