Description

Potassium (4-Methoxy-2-Methylphenyl)Trifluoroborate is an organotrifluoroborate salt, a highly valuable and stable synthetic intermediate in modern cross-coupling chemistry. Its primary value lies in its exceptional stability to air and moisture compared to traditional boronic acids, enabling easier handling and storage while maintaining high reactivity in key transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for Suzuki-Miyaura coupling reactions to create complex biaryl structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides that require specific biaryl motifs.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysts, and novel polymers.
• Chemical Biology & Medicinal Chemistry: Employed in the discovery and optimization of new chemical entities for biological screening and target identification.
• Scale-up Process Development: Ideal for transitioning from laboratory-scale discovery to pilot and commercial-scale manufacturing due to its handling stability.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical suppliers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	Potassium (4-Methoxy-2-Methylphenyl)Trifluoroborate
CAS No.	850623-69-7
Molecular Formula	C8H9BF3KO2
Molecular Weight	232.06 g/mol
Synonyms	Potassium (4-Methoxy-o-tolyl)trifluoroborate; Potassium Trifluoro(4-methoxy-2-methylphenyl)borate; (4-Methoxy-2-methylphenyl)trifluoroborate Potassium Salt; 4-Methoxy-2-methylphenyltrifluoroborate Potassium; 2-Methyl-4-methoxyphenyltrifluoroboronic Acid Potassium Salt; Potassium 4-Methoxy-2-methylbenzenetrifluoroborate; Borate(1-), trifluoro(4-methoxy-2-methylphenyl)-, potassium (1:1)
EINECS	Contact for details

Quality Control

Our Potassium (4-Methoxy-2-Methylphenyl)Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C), HPLC, and KF titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the primary container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR Purity	≥ 97.0%
Water Content (KF)	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.