Description

Potassium (2-Methylsulfonylphenyl)Trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling robust and selective cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing biaryl and heterobiaryl scaffolds prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular architecture is critical.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant boronic acid surrogate, offering superior handling and reactivity profiles compared to boronic acids.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry.
• Ligand and Catalyst Preparation: Used in the synthesis of complex organic ligands and catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Potassium (2-Methylsulfonylphenyl)Trifluoroborate
CAS No.	850623-65-3
Molecular Formula	C7H7BF3KO2S
Molecular Weight	250.10 g/mol
Synonyms	Potassium (2-(Methylsulfonyl)phenyl)trifluoroborate; 2-(Methylsulfonyl)phenyltrifluoroborate Potassium Salt; (2-Methanesulfonylphenyl)trifluoroboronic Acid Potassium Salt; Potassium 2-Methylsulfonylphenyltrifluoroborate; Potassium Trifluoro(2-(methylsulfonyl)phenyl)borate; 2-Methylsulfonylphenyl-BF3K; Potassium (2-Mesylphenyl)trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium (2-Methylsulfonylphenyl)Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 19F, 11B), HPLC for purity assessment, and KF titration for moisture content, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
NMR Purity (1H)	≥ 95.0%
Solubility Test	Soluble in common polar organic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.