Description

Potassium (3-Chloro-4-Fluorophenyl)Trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling robust and selective cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biaryl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Material Science Research: Serves as a building block for organic electronic materials, such as those used in OLEDs and semiconductors.
• Suzuki-Miyaura Cross-Coupling Reactions: The primary application, offering superior stability and handling compared to boronic acids, leading to higher yields and purity.
• Ligand and Catalyst Development: Employed in the research and development of new catalytic systems and chiral ligands.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.

Basic Information

Product Name	Potassium (3-Chloro-4-Fluorophenyl)Trifluoroborate
CAS No.	850623-59-5
Molecular Formula	C6H3BClF4K
Molecular Weight	227.44 g/mol
Synonyms	Potassium 3-Chloro-4-fluorophenyltrifluoroborate; (3-Chloro-4-fluorophenyl)trifluoroborate potassium salt; Potassium (3-Chloro-4-fluorophenyl)trifluoroboronate; 3-Chloro-4-fluorophenyltrifluoroboronic acid potassium salt; 3-Chloro-4-fluoro-Benzeneboronic Acid Trifluoroborate Potassium Salt; 3-Chloro-4-fluorophenyl-BF3K; Potassium Trifluoro(3-chloro-4-fluorophenyl)borate
EINECS	Contact for details

Quality Control

Every batch of Potassium (3-Chloro-4-Fluorophenyl)Trifluoroborate is manufactured and tested under strict quality management protocols to ensure consistency and high purity for critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, NMR purity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (NMR)	≥ 97%
Assay (Potentiometric Titration)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in polar aprotic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.