Description

Potassium (4-Benzyloxyphenyl)Trifluoroborate is an organotrifluoroborate salt, a highly valuable and stable synthetic intermediate in modern cross-coupling chemistry. Its primary value lies in its exceptional stability to air and moisture compared to traditional boronic acids, simplifying handling and storage while maintaining high reactivity in key transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for constructing complex biaryl and heterobiaryl structures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of carbon-carbon bonds between aryl/heteroaryl halides and this trifluoroborate, enabling the synthesis of biphenyl derivatives.
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of active pharmaceutical ingredients (APIs), particularly those containing a 4-benzyloxyphenyl moiety.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where specific biphenyl scaffolds are required for biological activity.
• Liquid Crystal & OLED Material Research: Employed in the synthesis of organic electronic materials and liquid crystal compounds that utilize rigid, conjugated aromatic systems.
• Polymer Chemistry: Can be utilized to introduce functional aromatic groups into polymer backbones or side chains via coupling reactions.
• Chemical Biology & Probe Development: Useful for bioconjugation and the synthesis of molecular probes for imaging and diagnostic applications.

Basic Information

Product Name	Potassium (4-Benzyloxyphenyl)Trifluoroborate
CAS No.	850623-47-1
Molecular Formula	C13H11BF3KO
Molecular Weight	290.13 g/mol
Synonyms	Potassium (4-(Benzyloxy)phenyl)trifluoroborate; 4-(Benzyloxy)phenyltrifluoroborate Potassium Salt; [4-(Phenylmethoxy)phenyl]trifluoroboronic Acid Potassium Salt; Potassium 4-Benzyloxyphenyltrifluoroborate; (4-Benzyloxyphenyl)trifluoroboronic Acid Potassium Salt; B-(4-(Benzyloxy)phenyl)trifluoroboronic Acid Potassium Salt; Potassium 4-(Benzyloxy)benzenetrifluoroboronate
EINECS	Contact for details

Quality Control

Our Potassium (4-Benzyloxyphenyl)Trifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term stability. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.