Description

Potassium (4-Cbz-Aminophenyl)Trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its stability and reactivity as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biphenyl or substituted phenyl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant boronic acid equivalent for palladium-catalyzed C-C bond formation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: A building block for constructing organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	Potassium (4-Cbz-Aminophenyl)Trifluoroborate
CAS No.	850623-45-9
Molecular Formula	C14H12BF3KNO2
Molecular Weight	333.16 g/mol
Synonyms	Potassium (4-(((Benzyloxy)carbonyl)amino)phenyl)trifluoroborate; Potassium N-Cbz-4-aminophenyltrifluoroborate; 4-(N-Cbz-Amino)phenyltrifluoroborate Potassium Salt; [4-(Benzyloxycarbonylamino)phenyl]trifluoroboronic Acid Potassium Salt; Potassium [(Benzyloxycarbonyl)amino]phenyltrifluoroborate; Potassium 4-(N-Carbobenzyloxyamino)phenyltrifluoroborate; K[C6H4(NHCbz)]BF3; Potassium 4-(Cbz-NH)-C6H4-BF3K
EINECS	Contact for details

Quality Control

Our Potassium (4-Cbz-Aminophenyl)Trifluoroborate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) to maintain stability and prevent decomposition. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
NMR Purity (1H/19F NMR)	Conforms
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.