Description

1-(4-Boronobenzoyl)Piperidine-4-Carboxylic Acid is a high-purity, multifunctional organic building block that integrates a boronic acid pinacol ester moiety with a piperidine carboxylic acid scaffold. This compound is critical for facilitating advanced cross-coupling reactions, particularly in the synthesis of complex pharmaceutical intermediates and novel materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and CNS drug discovery.
• Agrochemical Research: Used in the development of new herbicides and pesticides by enabling the introduction of complex aromatic systems into target molecules.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, due to its conjugated boronic ester functionality.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and affinity tags for studying enzyme function and protein interactions.
• Library Synthesis for Drug Discovery: A valuable reagent for parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.
• Ligand Synthesis for Catalysis: Used to prepare novel bidentate or tridentate ligands for transition metal catalysis.

Basic Information

Product Name	1-(4-Boronobenzoyl)Piperidine-4-Carboxylic Acid
CAS No.	850593-02-1
Molecular Formula	C14H18BNO5
Molecular Weight	291.11 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoylpiperidine-4-carboxylic acid; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl]piperidine-4-carboxylic acid; Piperidine-4-carboxylic acid, 1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl]-; 1-(4-Boronobenzoyl)-4-piperidinecarboxylic acid (pinacol ester); 850593-02-1; BCPC pinacol ester; 4-Carboxypiperidine boronic ester derivative.
EINECS	Contact for details

Quality Control

Our 1-(4-Boronobenzoyl)Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring high-purity building blocks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere or in a desiccator to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.