Description

3-Chloro-4-(n-Benzylcarbamoyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected amide moiety, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who are developing new active ingredients, particularly for creating complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting kinase inhibition or requiring specific biaryl scaffolds.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides with tailored activity profiles.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialized polymers and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The boronic acid functionality makes it an ideal partner for palladium-catalyzed coupling with aryl halides, a cornerstone reaction for C-C bond formation.
• Chemical Biology & Probe Development: Utilized in constructing molecular probes and sensors for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses producing complex, high-value organic molecules for clients.

Basic Information

Product Name	3-Chloro-4-(n-Benzylcarbamoyl)Phenylboronic Acid
CAS No.	850589-42-3
Molecular Formula	C14H13BClNO3
Molecular Weight	289.52 g/mol
Synonyms	[3-Chloro-4-[[(phenylmethyl)amino]carbonyl]phenyl]boronic acid; 3-Chloro-4-(benzylcarbamoyl)benzeneboronic acid; 3-Chloro-4-(N-benzylaminocarbonyl)phenylboronic acid; 4-Borono-2-chloro-N-benzylbenzamide; B-[3-Chloro-4-[(phenylmethyl)carbamoyl]phenyl]boronic acid; 850589-42-3; 3-Chloro-4-(benzylcarbamoyl)phenylboronic acid pinacol ester (common protected form)
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-(n-Benzylcarbamoyl)Phenylboronic Acid is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for critical synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas when possible to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.