Description

2-(4-Boronophenyl)-2-Methylpropanenitrile is a specialized boronic acid derivative featuring a nitrile functional group. This compound is a valuable building block in modern synthetic organic chemistry, particularly for cross-coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex aromatic scaffolds.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as polymers for OLEDs or OFETs.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological pathways and target engagement.
• Ligand and Catalyst Development: Acts as a starting material for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	2-(4-Boronophenyl)-2-Methylpropanenitrile
CAS No.	850568-67-1
Molecular Formula	C10H12BNO
Molecular Weight	173.02 g/mol
Synonyms	4-(2-Cyano-2-propyl)phenylboronic acid; 2-Methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanenitrile (pinacol ester); (4-(2-Cyano-2-propyl)phenyl)boronic acid; 2-(4-Boronophenyl)-2-methylpropionitrile; p-(2-Cyano-2-propyl)benzeneboronic acid; 850568-67-1; 2-(4-Boronophenyl)-2-methylpropanenitrile
EINECS	Contact for details

Quality Control

Our 2-(4-Boronophenyl)-2-Methylpropanenitrile is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.