Description

4-Aminomethylphenylboronic Acid, Pinacol Ester, Hcl is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in the dual functionality of the boronic ester group and the primary amine, which is stabilized as its hydrochloride salt for improved handling and shelf life. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for Suzuki-Miyaura cross-coupling reactions and as a precursor for bioactive molecule synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules via cross-coupling, enabling the development of new active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific aryl-alkyl linkages.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Bioconjugation & Probe Development: The amine and boronic acid functionalities allow for conjugation to biomolecules and the creation of sensors or diagnostic probes.
• Library Synthesis for Drug Discovery: Employed in high-throughput and combinatorial chemistry to generate diverse compound libraries for screening.
• Ligand & Catalyst Preparation: Used to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	4-Aminomethylphenylboronic Acid, Pinacol Ester, Hcl
CAS No.	850568-55-7
Molecular Formula	C13H21BClNO2
Molecular Weight	269.57 g/mol
Synonyms	4-(Aminomethyl)benzeneboronic Acid Pinacol Ester Hydrochloride; 1-[(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]benzylamine Hydrochloride; Benzenemethanamine, 4-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]-, hydrochloride; 4-(Pinacolatoborylmethyl)benzylamine Hydrochloride; 4-Aminomethylphenylboronic Acid Pinanediol Ester HCl (common alternative); 4-AMBP Pinacol Ester HCl; p-(Aminomethyl)phenylboronic Acid Pinacol Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our production of 4-Aminomethylphenylboronic Acid, Pinacol Ester, Hcl adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and commercial use. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent hydrolysis of the boronic ester moiety.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.