Description

1,4-Dioxa-Spiro[4.5]Dec-7-En-8-Boronic Acid is a versatile and high-value boronic acid derivative featuring a spirocyclic acetal-protected diol and an alkene moiety. This compound is a critical advanced pharmaceutical intermediate (API) and a key building block in modern synthetic chemistry, prized for its ability to participate in cross-coupling reactions like the Suzuki-Miyaura reaction. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors who require precise, high-purity intermediates for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring spirocyclic or functionalized ring systems.
• Suzuki-Miyaura Cross-Coupling: Serves as a crucial boron-containing coupling partner for constructing carbon-carbon bonds in medicinal chemistry and material science.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides with specific activity profiles.
• Ligand and Catalyst Development: Employed as a building block for creating novel chiral ligands and organometallic catalysts.
• Material Science Research: A monomer or precursor for synthesizing specialized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors due to its reactive boronic acid group.

Basic Information

Item	Details
Product Name	1,4-Dioxa-Spiro[4.5]Dec-7-En-8-Boronic Acid
CAS No.	850567-90-7
Molecular Formula	C9H13BO4
Molecular Weight	196.01 g/mol
Synonyms	7-Boronic Acid-1,4-dioxaspiro[4.5]dec-7-ene; 1,4-Dioxaspiro[4.5]dec-7-ene-8-boronic acid; 8-Borono-1,4-dioxaspiro[4.5]dec-7-ene; 1,4-Dioxa-8-boraspironon-6-ene; Spirocyclic acetal-protected boronic acid; (1,4-Dioxaspiro[4.5]dec-7-en-8-yl)boronic acid; 7-Borono-1,4-dioxaspiro[4.5]dec-7-ene
EINECS	Contact for details

Quality Control

Our 1,4-Dioxa-Spiro[4.5]Dec-7-En-8-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to maximize long-term stability, as boronic acids can be sensitive to prolonged air exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.