Description

1-Butyl-3-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is a high-value, organoboron building block critical for modern synthetic chemistry. This compound matters as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel chemical entities via Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific boron-containing scaffolds.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and tools for studying biological systems and target engagement.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds with high efficiency and selectivity.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry programs.

Basic Information

Product Name	1-Butyl-3-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea
CAS No.	850567-59-8
Molecular Formula	C₁₇H₂₇BN₂O₃
Molecular Weight	318.22 g/mol
Synonyms	1-Butyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; N-Butyl-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylurea butyl derivative; Urea, N-butyl-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; B-[4-[(Butylamino)carbonyl]amino]phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Butyl-3-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.