Description

1-(4-Chlorophenyl)Vinylboronic Acid, Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific chlorophenyl-vinyl motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes for biological target identification.
• Ligand & Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CROs/CMOs serving the life sciences sector.

Basic Information

Product Name	1-(4-Chlorophenyl)Vinylboronic Acid, Pinacol Ester
CAS No.	850567-54-3
Molecular Formula	C14H18BClO2
Molecular Weight	264.55 g/mol
Synonyms	1-(4-Chlorophenyl)ethenylboronic acid pinacol ester; (1-(4-Chlorophenyl)vinyl)boronic acid pinacol ester; 4-Chlorostyrylboronic acid pinacol ester; (2-(4-Chlorophenyl)vinyl)boronic acid pinacol ester; 1-(p-Chlorophenyl)vinylboronic acid pinacol ester; B-[1-(4-Chlorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 850567-54-3; Pinacol (1-(4-chlorophenyl)vinyl)boronate
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)Vinylboronic Acid, Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity, purity, and the absence of critical metallic impurities like palladium. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (argon or nitrogen) in a sealed container with desiccant to maintain optimal stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.