Description

3-Amino-4-Methylphenylboronic Acid, Pinacol Ester, Hcl is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, making it a superior reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex biaryl and heterobiaryl structures central to active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex aryl-aryl linkages.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific biaryl motifs.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Amino-4-Methylphenylboronic Acid, Pinacol Ester, Hcl
CAS No.	850567-52-1
Molecular Formula	C13H21BClNO2
Molecular Weight	269.57 g/mol
Synonyms	3-Amino-4-methylbenzeneboronic acid pinacol ester hydrochloride; 2-(3-Amino-4-methylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane hydrochloride; (3-Amino-4-methylphenyl)boronic acid pinacol ester hydrochloride; 3-Amino-p-tolylboronic acid pinacol ester HCl; Boronic acid, B-(3-amino-4-methylphenyl)-, 1,1-dimethylethyl ester, hydrochloride; CAS 850567-52-1
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-4-Methylphenylboronic Acid, Pinacol Ester, Hcl is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.