Description

n-Methylpyrrole-2-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic organic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing drug candidates containing substituted pyrrole motifs.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its stability and reactivity to create complex molecular architectures.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes for biological target identification.
• Academic & Contract Research: A staple reagent in university and CRO laboratories for methodological development and the synthesis of complex natural product analogs.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale synthesis due to its defined purity and stability profile.

Basic Information

Product Name	n-Methylpyrrole-2-Boronic Acid, Pinacol Ester
CAS No.	850567-47-4
Molecular Formula	C11H18BNO2
Molecular Weight	207.08 g/mol
Synonyms	1-Methyl-1H-pyrrol-2-ylboronic acid pinacol ester; 1-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methylpyrrole; N-Methyl-2-pyrrolylboronic acid pinacol ester; 1-Methyl-2-pyrrolylboronic acid pinacol ester; Boronic acid, B-(1-methyl-1H-pyrrol-2-yl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our n-Methylpyrrole-2-Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to meet the exacting standards of research and industrial synthesis. Each batch is analyzed using advanced techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with your internal quality systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.