Description

3-Aminobenzeneboronic Acid, Neopentyl Glycol Ester Hydrochloride is a high-purity, protected boronic acid derivative, essential for advanced organic synthesis. This compound is a critical building block in modern pharmaceutical and agrochemical research, offering enhanced stability and reactivity for cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to create complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, polymers, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed as a tool compound for bioconjugation and the development of enzyme inhibitors or activity-based probes.
• Catalyst Ligand Synthesis: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke, high-value fine chemicals under cGMP conditions.

Basic Information

Product Name	3-Aminobenzeneboronic Acid, Neopentyl Glycol Ester Hydrochloride
CAS No.	850567-43-0
Molecular Formula	C13H21BClNO2
Molecular Weight	269.57 g/mol
Synonyms	3-Aminophenylboronic Acid Neopentyl Glycol Ester Hydrochloride; (3-Aminophenyl)boronic Acid Neopentyl Ester Hydrochloride; 3-Aminobenzeneboronic Acid Pinanediol Ester Hydrochloride (common analog); B-(3-Aminophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Hydrochloride; 3-Amino Phenyl Boronic Acid NPG Ester HCl; 3-APBA-NPG Ester HCl; Boronic Ester of 3-Aminobenzoic Acid Hydrochloride; 850567-43-0
EINECS	Contact for details

Quality Control

Our 3-Aminobenzeneboronic Acid, Neopentyl Glycol Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.