Description

4,5-Difluorooxindole is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the difluorooxindole core contributes to enhanced efficacy and environmental profile.
• Material Science Research: Serves as a building block for novel organic electronic materials and functional dyes due to its electron-rich heterocyclic structure.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4,5-Difluorooxindole
CAS No.	850429-64-0
Molecular Formula	C8H5F2NO
Molecular Weight	169.13 g/mol
Synonyms	4,5-Difluoro-1,3-dihydro-2H-indol-2-one; 4,5-Difluoro-2-indolinone; 4,5-Difluorooxindole; 1,3-Dihydro-4,5-difluoro-2H-indol-2-one; 2H-Indol-2-one, 1,3-dihydro-4,5-difluoro-; 850429-64-0; 4,5-Difluoroindolin-2-one
EINECS	Contact for details

Quality Control

Our 4,5-Difluorooxindole is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.